Aladdin™ BS(PEG)5 , CAS No.A638726

  • Molecular Weight:  532.5
In stock
Item Number
A638726
Grouped product items
SKU Size Availability Price Qty
A638726-10×1mg
10×1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$633.90
A638726-100mg
100mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$916.90

BS(PEG)5

Basic Description

Storage Temp Store at -20°C,Desiccated
Shipped In Ice chest + Ice pads
Product Description

Product introduction:

BS(PEG)5 is a bis-succinimide ester-activated PEG compound used for crosslinking between primary amines (—NH2) in proteins and other molecules. The N-hydroxysuccinimide ester (NHS) groups at either end of the PEG5 spacer react specifically and efficiently with lysine and N-terminal amino groups at pH 7-9 to form stable amide bonds.

No-Weigh products are specialty reagents provided in a pre-aliquoted format. The pre-weighed packaging prevents the loss of reagent reactivity and contamination over time by eliminating the repetitive opening and closing of the vial. The format enables use of a fresh vial of reagent each time, eliminating the hassle of weighing small amounts of reagents and reducing concerns over reagent stability.

Features of BS(PEG)5:

Reactive groups:sulfo-NHS ester (both ends)
Reactive towards: amino groups (primary amines)
• NHS esters react with—NH2 groups at pH 7-9, forming stable amide bonds
• Water-soluble; compare to non-pegylatedBS3 (also soluble) andDSS (water-insoluble)
• Membrane-impermeable, allowing for cell surface labeling
• Irreversibly crosslink proteins or peptides by flexible PEG spacer arms
• Polyethylene glycol spacer arms help maintain conjugate solubility
• Pure compound with defined structure and molecular weight, ensuring reproducible protein-modification effects
• PEG spacer provides unique advantages, including increased stability, reduced tendency toward aggregation and reduced immunogenicity
• Ideal for small molecule or peptide conjugations

Alternative Names for BS(PEG)n:

• Bis-NHS-dPEG
• NHS-PEG-NHS
• BS(PEO)5
• Bis(NHS)PEO5
• BS-PEO9
• dPEG NHS ester
• Bis-succinimide ester PEG 400

Product References
Crosslinker Application Guide -- search for recent literature references for this product

Reactive Moiety:Sulfo-NHS Ester

Crosslinker Type:Homobifunctional

Form:Powder

Spacer:Medium(10 to 30 Å)

Labeling Method:Chemical Labeling

Spacer Arm Length:21.7 Å

AI Insight

Product Properties

Reactivity Amine-Amine

Names and Identifiers

Molecular Weight 532.5

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Chemical and Physical Properties

Solubility Water

Specifications

Solution Calculators

Reviews

Customer Reviews

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