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  1. , Macrophage colony stimulating factor receptor inhibitor
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    Seralutinib (GB002), Macrophage colony stimulating factor receptor inhibitor
    Cas#: 1619931-27-9        Compound CID:  91663352
    Formula:  C27H27N5O3        Molecular Weight: 469.54
    IUPAC Name: N-[3-[(1S)-1-[[6-(3,4-dimethoxyphenyl)pyrazin-2-yl]amino]ethyl]phenyl]-5-methylpyridine-3-carboxamide
    SMILES: CC1=CC(=CN=C1)C(=O)NC2=CC=CC(=C2)C(C)NC3=NC(=CN=C3)C4=CC(=C(C=C4)OC)OC
    InChIKey: JHJNPOSPVGRIAN-SFHVURJKSA-N
    InChI: InChI=1S/C27H27N5O3/c1-17-10-21(14-28-13-17)27(33)31-22-7-5-6-19(11-22)18(2)30-26-16-29-15-23(32-26)20-8-9-24(34-3)25(12-20)35-4/h5-16,18H,1-4H3,(H,30,32)(H,31,33)/t18-/m0/s1
    Synonyms: GTPL10618 | UNII-3P63ZTE3OY | SERALUTINIB [WHO-DD] | 3P63ZTE3OY | HY-109190 | AT11371 | Seralutinib | EX-A5138 | MS-2...
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  2. , Inhibitor of FKBP prolyl isomerase 1A;Activator of TRPM8
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    Tacrolimus（anhydrous）(FK506), Inhibitor of FKBP prolyl isomerase 1A;Activator of TRPM8
    Cas#: 104987-11-3        Compound CID:  445643
    Formula:  C44H69NO12        Molecular Weight: 804.02
    IUPAC Name: (1R,9S,12S,13R,14S,17R,18E,21S,23S,24R,25S,27R)-1,14-dihydroxy-12-[(E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-23,25-dimethoxy-13,19,21,27-tetramethyl-17-prop-2-enyl-11,28-dioxa-4-azatricyclo[22.3.1.04,9]octacos-18-ene-2,3,10,16-tetrone
    SMILES: CC1CC(C2C(CC(C(O2)(C(=O)C(=O)N3CCCCC3C(=O)OC(C(C(CC(=O)C(C=C(C1)C)CC=C)O)C)C(=CC4CCC(C(C4)OC)O)C)O)C)OC)OC
    InChIKey: QJJXYPPXXYFBGM-LFZNUXCKSA-N
    InChI: InChI=1S/C44H69NO12/c1-10-13-31-19-25(2)18-26(3)20-37(54-8)40-38(55-9)22-28(5)44(52,57-40)41(49)42(50)45-17-12-11-14-32(45)43(51)56-39(29(6)34(47)24-35(31)48)27(4)21-30-15-16-33(46)36(23-30)53-7/h10,19,21,26,28-34,36-40,46-47,52H,1,11-18,20,22-24H2,2-9H3/b25-19+,27-21+/t26-,28+,29+,30-,31+,32-,33+,34-,36+,37-,38-,39+,40+,44+/m0/s1
    Synonyms: (7aR)-4,4,7a-trimethyl-6,7-dihydro-5H-benzofuran-2-one;Dihydroactinidiolide | CHEBI:93221 | DB00864 | HMS1792O21 | UN...
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    FKBP1A
  2. Target
    PRKCZ
  3. Target
    PDGFRB
  4. Purity
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  1. CYP1A2 12 items
  2. CA12 12 items
  3. CA7 11 items
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  86. SLCO1A2 1 item
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  90. TAS2R10 1 item
  91. TAS2R20 1 item
  92. TAS2R8 1 item
  93. SNCA 1 item
  94. TERT 1 item
  95. TRPV4 1 item
  96. PMVK 1 item
  97. PIN1 1 item
  98. PDGFRA 1 item
  99. PDGFRB 1 item
  100. RARB 1 item
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  103. F2RL1 1 item
  104. RGS17 1 item
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  106. RPS6KA1 1 item
  107. RPS6KA2 1 item
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  110. MMP12 1 item
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  113. GLO1 1 item
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  115. NR1H4 1 item
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  120. BCL2 1 item
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  125. APEX1 1 item
  126. HTR2A 1 item
  127. HTR1E 1 item
  128. HTR7 1 item
  129. ADRA1B 1 item
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  131. ALB 1 item
  132. ADRA1D 1 item
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  135. AR 1 item
  136. MAOB 1 item
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  138. HTR1D 1 item
  139. HTR1F 1 item
  140. APP 1 item
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  143. CHEK1 1 item
  144. CLK1 1 item
  145. CISD1 1 item
  146. H1F0 1 item
  147. GANAB 1 item
  148. IMPDH2 1 item
  149. IMPDH1 1 item
  150. PTAFR 1 item
  151. PPARD 1 item
  152. PPP3CA 1 item
  153. NOX4 1 item
  154. IL2 1 item
  155. IL6 1 item
  156. RPS6KA3 1 item
  157. MAP2K1 1 item
  158. CDC25B 1 item
  159. NISCH 1 item
  160. MTOR 1 item
  161. PRKCZ 0 items
Grade
  1. Moligand™ 2 items
  2. analytical standard 1 item
Action Type
  1. INHIBITOR 2 items
  2. ACTIVATOR 1 item
Molecule Type
  1. Small molecule 1 item
Purity
  1. ≥98% 2 items
  2. ≥99%(GC) 1 item
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