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DOTAP Transfection Reagent - 1 mg/ml in MES-buffered saline, high purity , CAS No.144189-73-1

1 Citations

1 mg/ml in MES-buffered saline

CAS#: 144189-73-1
Molecular Weight: 774.19
PubChem CID: 16218742

In stock

Item Number

D353304

Grouped product items
SKU	Size	Availability	Price	Qty
D353304-400μl	400μl	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$156.90

a cationic lipid formulation used for transfection of DNA, RNA, and YAC.

Basic Description

Synonyms	CS-0185615 \| DOTAP \| 18:1 TAP (DOTAP, MS Salt), 1,2-dioleoyl-3-trimethylammonium-propane (methyl sulfate salt), chloroform \| N,N,N-Trimethyl-2,3-bis(oleoyloxy)propan-1-aminium methyl sulfate \| DOTAP Liposomal Transfection Reagent, N-[1-(2,3-Dioleoyloxy)pr
Specifications & Purity	1 mg/ml in MES-buffered saline
Storage Temp	Store at 2-8°C
Shipped In	Wet ice
Product Description	DOTAP Transfection Reagent is a liposomal formulation of the cationic lipid DOTAP. DOTAP Transfection Reagent is used not only for DNA and RNA transfection, but yeast artificial chromosomes (YAC) as well, with or without serum. This transfection via DOTAP Transfection Reagent is between eukaryotic cells in iehter transient or stable gene expression. DOTAP Transfection Reagent is also suitable for other negatively charged molecules, including oligonucleotidees and glutamic acid.

Names and Identifiers

IUPAC Name	2,3-bis[[(Z)-octadec-9-enoyl]oxy]propyl-trimethylazanium;methyl sulfate
INCHI	InChI=1S/C42H80NO4.CH4O4S/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-41(44)46-39-40(38-43(3,4)5)47-42(45)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2;1-5-6(2,3)4/h20-23,40H,6-19,24-39H2,1-5H3;1H3,(H,2,3,4)/q+1;/p-1/b22-20-,23-21-;
InChi Key	RSMRWWHFJMENJH-LQDDAWAPSA-M
Canonical SMILES	CCCCCCCCC=CCCCCCCCC(=O)OCC(C[N+](C)(C)C)OC(=O)CCCCCCCC=CCCCCCCCC.COS(=O)(=O)[O-]
Isomeric SMILES	CCCCCCCC/C=C\CCCCCCCC(=O)OCC(C[N+](C)(C)C)OC(=O)CCCCCCC/C=C\CCCCCCCC.COS(=O)(=O)[O-]
WGK Germany	3
PubChem CID	16218742
Molecular Weight	774.19

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Chemical and Physical Properties

Molecular Weight	774.200 g/mol
XLogP3
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	37
Exact Mass	773.584 Da
Monoisotopic Mass	773.584 Da
Topological Polar Surface Area	127.000 Å²
Heavy Atom Count	53
Formal Charge	0
Complexity	845.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	1
Defined Bond Stereocenter Count	2
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	2
Covalently-Bonded Unit Count	2

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Yandong Xie, Xueying Lu, Zhen Wang, Mingxi Liu, Liang Liu, Ran Wang, Kun Yang, Hong Xiao, Jianyong Li, Xianglong Tang, Hongyi Liu. (2022) A hypoxia-dissociable siRNA nanoplatform for synergistically enhanced chemo-radiotherapy of glioblastoma. Biomaterials Science, 10 (23): (6791-6803). [PMID:36314541] [10.1039/D2BM01145J]

References

1. Yandong Xie, Xueying Lu, Zhen Wang, Mingxi Liu, Liang Liu, Ran Wang, Kun Yang, Hong Xiao, Jianyong Li, Xianglong Tang, Hongyi Liu. (2022) A hypoxia-dissociable siRNA nanoplatform for synergistically enhanced chemo-radiotherapy of glioblastoma. Biomaterials Science, 10 (23): (6791-6803). [PMID:36314541] [10.1039/D2BM01145J]

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DOTAP Transfection Reagent - 1 mg/ml in MES-buffered saline, high purity , CAS No.144189-73-1

Basic Description

AI Insight

Names and Identifiers

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

Chemical and Physical Properties

Safety and Hazards(GHS)

Specifications