Articles by tag "Azide-Alkyne Click Chemistry"

1. PEG-Azide-Alkyne—Bioorthogonal and Click Chemistry
   posted this at Jun 5, 2025

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   Bioorthogonal chemistry refers to a series of reactions that occur in a biological environment without affecting biomolecules or interfering with biochemical processes. For this purpose, the reaction must meet the following requirements: fast, efficient, and specific. • pH: The reaction must ...
2. Recent Advances in the Catalytic Transformations to Access Alkylsulfonyl Fluorides as SuFEx Click Hubs
   posted this at Jun 5, 2025

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   The quest for innovative and effective techniques to produce sulfonyl fluorides is of significant interest due to their extensive applications across various fields. Sulfur(VI) fluoride exchange (SuFEx) click chemistry has recently gained prominence as one of the leading methods in this domain. ...
3. Azide-Alkyne Click Chemistry
   posted this at Jun 5, 2025

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   Classic Click Chemistry uses copper, Cu(I), to catalyze the 1,3-dipolar cycloaddition of an alkyne with an azide to form a 1,2,3-triazole.1,2 Sources of Cu(I) include copper(I) iodide, copper(I) bromide, copper turnings, or copper (II) sulfate (CuSO4) and a reducing agent.1 However, the ...