Chloramine-T is a source of electrophilic chlorine. In water, chloramine-T is decomposed to yield hypochlorite, which acts as a disinfectant, and the sulfonamide moiety, which inhibits bacterial grow due to the similarity with para-aminobenzoic acid (a bacterial metabolite). Chloramine-T can ...
The use of chloramine-B as the oxidant and KI or NaBr as the halogen source enables a direct oxidative halogenation of terminal alkynes to provide synthetically valuable 1-iodoalkynes and 1-bromoalkynes in very good yields under mild reaction conditions.
In the field of organic chemistry, halogenation reactions and their products - halogenation compounds - do play a crucial role. These reactions not only enrich the toolbox of organic synthesis, but also greatly expand the application range of halogenation compounds in complex molecular ...
