Basic Description

Synonyms	DTXSID70192769 \| 2-methylmercaptoimidazoline hydroiodide \| Lysine monohydrate \| AKOS005145556 \| CS-W016086 \| L-Lysine, hydrate \| L-Lysine, hydrate (1:x) \| AS-13538 \| But-3-ynylamine hydrochloride, AldrichCPR \| A824685 \| AM81902 \| L-Lysine monohydrate, pur
Specifications & Purity	BioReagent, for cell culture, Animal Free
Biochemical and Physiological Mechanisms	L-Lysine is an essential proteinogenic α amino acid used in a wide range of applications including as a non-animal sourced supplement in cell culture media, a substrate of enzymes such as L-lysine oxidase (EC 1.4.3.14), a component of poly-lysine polymers
Grade	Animal Free, BioReagent, for cell culture
Product Description	L-Lysine is an amino acid with a basic side chain and is amphipathic in nature. It has a protonated alkyl amino group and is fully protonated at physiological pH. L-lysine mainly participates in electrostatic interactions in proteins.L-Lysine monohydrate has been used in:SILAC (stable isotope labeling by amino acids in cell culture) methodthe complete synthetic (C) medium for positive selection screening of yeast cellsthe growth medium for cells

AI Insight

Names and Identifiers

Pubchem Sid	504768144
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/504768144
IUPAC Name	(2S)-2,6-diaminohexanoic acid;hydrate
INCHI	InChI=1S/C6H14N2O2.H2O/c7-4-2-1-3-5(8)6(9)10;/h5H,1-4,7-8H2,(H,9,10);1H2/t5-;/m0./s1
InChi Key	HZRUTVAFDWTKGD-JEDNCBNOSA-N
Canonical SMILES	C(CCN)CC(C(=O)O)N.O
Isomeric SMILES	C(CCN)C[C@@H](C(=O)O)N.O
WGK Germany	3
PubChem CID	16211825
Molecular Weight	164.2
Beilstein	4349963

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

6 results found

Lot Number	Certificate Type	Date	Item
H2309064	Certificate of Analysis	Jul 17, 2023	L478519
H2309068	Certificate of Analysis	Jul 17, 2023	L478519
H2309073	Certificate of Analysis	Jul 17, 2023	L478519
H2309072	Certificate of Analysis	Jul 17, 2023	L478519
H2309079	Certificate of Analysis	Jul 17, 2023	L478519
H2309078	Certificate of Analysis	Jul 17, 2023	L478519

Chemical and Physical Properties

Solubility	H2O: soluble
Specific Rotation[α]	+22°,c = 2 in 6 M HCl
Melt Point(°C)	210°C
Molecular Weight	164.200 g/mol
XLogP3
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	5
Exact Mass	164.116 Da
Monoisotopic Mass	164.116 Da
Topological Polar Surface Area	90.300 Å²
Heavy Atom Count	11
Formal Charge	0
Complexity	106.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	1
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	2

Safety and Hazards(GHS)

WGK Germany	3

Specifications

Specification Sheet

FAQs and Articles

FAQ

Guidelines For Common Cell Culture Media

Categories: Technical articles

Tags:

Biological buffer Cell medium raw materials Cell culture additives Amino acids Vitamins Growth factors Salt Glucose Nucleosides & nucleotides Carbs Cell culture and transfection

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Zhang Gaoyu, Sang Laifa, Xu Guogang, Dou Yajie, Wang Xinzhen. (2020) Synthesis and characterization of meso-porous Au-modified SnO2 fibers using natural silk with enhanced sensitivity for n-butanol. JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS, 31 (11): (8220-8229). [PMID:] [10.1007/s10854-020-03357-z]
2. Shihua Yu, Zhigang Liu, Jianpo Zhang, Hongwei Li, Na Xu, Xin-xin Yuan, Yuqing Wu. (2018) An azo-coupling reaction-based surface enhanced resonance Raman scattering approach for ultrasensitive detection of salbutamol. RSC Advances, 8 (10): (5536-5541). [PMID:35542390] [10.1039/C7RA12927K]

References

1. H Kusakabe,K Kodama,A Kuninaka,H Yoshino,H Misono,K Soda. (1980-02-10) A new antitumor enzyme, L-lysine alpha-oxidase from Trichoderma viride. Purification and enzymological properties.. The Journal of biological chemistry, 255 ((3)): (976-981). [PMID:6101334]
2. Daniel Gómez,Patricia Lucas-Elío,Antonio Sanchez-Amat,Francisco Solano. (2006-10-13) A novel type of lysine oxidase: L-lysine-epsilon-oxidase.. Biochimica et biophysica acta, 1764 ((10)): (1577-1585). [PMID:17030025]
3. Hideaki Endo,Yoshitaka Hayashi,Yoichiro Kitani,Huifeng Ren,Tetsuhito Hayashi,Yuji Nagashima. (2008-02-01) Optical enzyme sensor for determining L-lysine content using L-lysine oxidase from the rockfish Sebastes schlegeli.. Analytical and bioanalytical chemistry, 391 ((4)): (1255-1261). [PMID:18236032]
4. Benjamin Newcomb,Antonio Bedalov. (2009-06-13) Identification of inhibitors of chromatin modifying enzymes using the yeast phenotypic screens.. Methods in molecular biology (Clifton, N.J.), 548 (145-160). [PMID:19521823]
5. Xiu-Min Chen,David D Kitts. (2011-09-23) Antioxidant and anti-inflammatory activities of Maillard reaction products isolated from sugar-amino acid model systems.. Journal of agricultural and food chemistry, 59 ((20)): (11294-11303). [PMID:21936573]
6. Gong Zhang,Guangwei Huang,Lu Xiao,Alyson E Mitchell. (2011-10-11) Determination of advanced glycation endproducts by LC-MS/MS in raw and roasted almonds (Prunus dulcis).. Journal of agricultural and food chemistry, 59 ((22)): (12037-12046). [PMID:21980977]
7. Dong Hoon Han, Hee-Kyung Na, Won Hoon Choi, Jung Hoon Lee, Yun Kyung Kim, Cheolhee Won, Seung-Han Lee, Kwang Pyo Kim, Jeff Kuret, Dal-Hee Min, Min Jae Lee,. (2014-12-06) Direct cellular delivery of human proteasomes to delay tau aggregation.. Nature communications, ( 5633-5633 ). [PMID:25476420]
8. Natalia A Cherepanova,Sergey V Venev,John D Leszyk,Scott A Shaffer,Reid Gilmore. (2019-07-13) Quantitative glycoproteomics reveals new classes of STT3A- and STT3B-dependent N-glycosylation sites.. The Journal of cell biology, 218 ((8)): (2782-2796). [PMID:31296534]
9. Mark Jelcic,Ke Wang,King Lam Hui,Xiao-Chuan Cai,Balázs Enyedi,Minkui Luo,Philipp Niethammer. (2020-06-11) A Photo-clickable ATP-Mimetic Reveals Nucleotide Interactors in the Membrane Proteome.. Cell chemical biology, 27 ((8)): (1073-1083). [PMID:32521230]
10. Jenna K Rimel,Zachary C Poss,Benjamin Erickson,Zachary L Maas,Christopher C Ebmeier,Jared L Johnson,Tim-Michael Decker,Tomer M Yaron,Michael J Bradley,Kristin B Hamman,Shanhu Hu,Goran Malojcic,Jason J Marineau,Peter W White,Martine Brault,Limei Tao,Patrick DeRoy,Christian Clavette,Shraddha Nayak,Leah J Damon,Ines H Kaltheuner,Heeyoun Bunch,Lewis C Cantley,Matthias Geyer,Janet Iwasa,Robin D Dowell,David L Bentley,William M Old,Dylan J Taatjes. (2020-10-17) Selective inhibition of CDK7 reveals high-confidence targets and new models for TFIIH function in transcription.. Genes & development, 34 ((21-22)): (1452-1473). [PMID:33060135]
11. W L McKeehan,W G Hamilton,R G Ham. (1976-06-01) Selenium is an essential trace nutrient for growth of WI-38 diploid human fibroblasts.. Proceedings of the National Academy of Sciences of the United States of America, 73 ((6)): (2023-2027). [PMID:1064872]
12. Shao-En Ong,Matthias Mann. (2007-04-05) A practical recipe for stable isotope labeling by amino acids in cell culture (SILAC).. Nature protocols, 1 ((6)): (2650-2660). [PMID:17406521]
13. Stefan W Vetter,Venkata S K Indurthi. (2011-08-13) Moderate glycation of serum albumin affects folding, stability, and ligand binding.. Clinica chimica acta; international journal of clinical chemistry, 412 ((23-24)): (2105-2116). [PMID:21835170]
14. Daniel Kalb,Gerald Lackner,Marcus Rappe,Dirk Hoffmeister. (2015-05-13) Activity of α-Aminoadipate Reductase Depends on the N-Terminally Extending Domain.. Chembiochem : a European journal of chemical biology, 16 ((10)): (1426-1430). [PMID:25965424]
15. Renfeng Li,Gangling Liao,Raja Sekhar Nirujogi,Sneha M Pinto,Patrick G Shaw,Tai-Chung Huang,Jun Wan,Jiang Qian,Harsha Gowda,Xinyan Wu,Dong-Wen Lv,Kun Zhang,Srikanth S Manda,Akhilesh Pandey,S Diane Hayward. (2015-12-30) Phosphoproteomic Profiling Reveals Epstein-Barr Virus Protein Kinase Integration of DNA Damage Response and Mitotic Signaling.. PLoS pathogens, 11 ((12)): (e1005346-e1005346). [PMID:26714015]
16. Zhang Gaoyu, Sang Laifa, Xu Guogang, Dou Yajie, Wang Xinzhen. (2020) Synthesis and characterization of meso-porous Au-modified SnO2 fibers using natural silk with enhanced sensitivity for n-butanol. JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS, 31 (11): (8220-8229). [PMID:] [10.1007/s10854-020-03357-z]
17. Shihua Yu, Zhigang Liu, Jianpo Zhang, Hongwei Li, Na Xu, Xin-xin Yuan, Yuqing Wu. (2018) An azo-coupling reaction-based surface enhanced resonance Raman scattering approach for ultrasensitive detection of salbutamol. RSC Advances, 8 (10): (5536-5541). [PMID:35542390] [10.1039/C7RA12927K]

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SKU	Size	Availability	Price
L478519-25g	25g	2	$539.90
L478519-100g	100g	1	$2,260.90
L478519-500g	500g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$10,170.90

L-Lysine monohydrate - BioReagent, suitable for cell culture, from non-animal source, high purity , CAS No.39665-12-8