Protein Degrader Building Blocks

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  1. Quinuclidin-3-yl acetate, Agonist of M 1 receptor;Agonist of M 2 receptor;Agonist of M 3 receptor;Agonist of M 4 receptor;Agonist of M 5 receptor
    Cas#: 827-61-2        Compound CID:  1979
    Formula:  C9H15NO2        Molecular Weight: 169.22
    IUPAC Name: 1-azabicyclo[2.2.2]octan-3-yl acetate
    SMILES: CC(=O)OC1CN2CCC1CC2
    InChIKey: WRJPSSPFHGNBMG-UHFFFAOYSA-N
    InChI: InChI=1S/C9H15NO2/c1-7(11)12-9-6-10-4-2-8(9)3-5-10/h8-9H,2-6H2,1H3
    Synonyms: 1-azabicyclo[2.2.2]octan-3-yl acetate | 3-Acetoxyquinuclidine | NSC657843 | aceclidine | 3-quinuclidinyl acetate | Gl...
  2. Tolterodine L-tartrate, Antagonist of M 1 receptor;Antagonist of M 2 receptor;Antagonist of M 3 receptor;Antagonist of M 4 receptor;Antagonist of M 5 receptor
    Cas#: 124937-51-5        Compound CID:  443879
    Formula:  C22H31NO        Molecular Weight: 325.5
    IUPAC Name: 2-[(1R)-3-[di(propan-2-yl)amino]-1-phenylpropyl]-4-methylphenol
    SMILES: CC1=CC(=C(C=C1)O)C(CCN(C(C)C)C(C)C)C2=CC=CC=C2
    InChIKey: OOGJQPCLVADCPB-HXUWFJFHSA-N
    InChI: InChI=1S/C22H31NO/c1-16(2)23(17(3)4)14-13-20(19-9-7-6-8-10-19)21-15-18(5)11-12-22(21)24/h6-12,15-17,20,24H,13-14H2,1-5H3/t20-/m1/s1
    Synonyms: DB01036 | Q-200223 | 2-((1R)-3-(diisopropylamino)-1-phenylpropyl)-4-methylphenol | MLS001195620 | OOGJQPCLVADCPB-HXUW...
  3. LY2033298, Allosteric modulator of M 2 receptor;Allosteric modulator of M 4 receptor
    Cas#: 886047-13-8        Compound CID:  11536903
    Formula:  C13H14ClN3O2S        Molecular Weight: 311.79
    IUPAC Name: 3-amino-5-chloro-N-cyclopropyl-6-methoxy-4-methylthieno[2,3-b]pyridine-2-carboxamide
    SMILES: CC1=C2C(=C(SC2=NC(=C1Cl)OC)C(=O)NC3CC3)N
    InChIKey: CTEGQKDJTBWFHW-UHFFFAOYSA-N
    InChI: InChI=1S/C13H14ClN3O2S/c1-5-7-9(15)10(11(18)16-6-3-4-6)20-13(7)17-12(19-2)8(5)14/h6H,3-4,15H2,1-2H3,(H,16,18)
    Synonyms: 3-Amino-5-chloro-N-cyclopropyl-6-methoxy-4-methylthieno(2,3-b)pyridine-2-carboxamide | IUE | LY2033298, >=98% (HPLC) ...
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